MuscleX 4 Symposium:
Sarcomeric regulation mechanisms in health and disease
We are pleased to announce the fourth BioCAT MuscleX symposium. The Biophysics Collaborative Access Team (BioCAT), funded by the National Institutes of Health (NIH), operates state-of-the-art X-ray facilities for studying the structure and dynamics of biological systems under non-crystalline conditions, resembling their functional states in living tissues. The symposium will feature an introductory presentation on BioCAT’s scientific missions, new capabilities enabled by recent upgrades to the APS source and to the BioCAT beamline, and a series of talks highlighting recent muscle studies utilizing X-ray diffraction or other structural techniques.
The workshop will take place from 5/15/2025 to 5/16/2025 and will be entirely virtual (via Zoom: https://iit-edu.zoom.us/meeting/register/tup-TPN-RS2g_pqBKHSQ5w).

Registration
All participants this year will attend remotely. There is no cost associated with the symposium, but registration (Registration Link) is required for administrative purposes.
More information
Symposium topics:
Introduction to the scientific mission at BioCAT
Scientific presentations from recent muscle studies using x-ray diffraction and/or other structural techniques:
- Thick filament structure and regulation
- Titin and MyBPC in muscle regulation
- Translational studies on structural bases of muscle diseases
If you have questions, please contact Maicon Landim Vieira (mlandimvieira@iit.edu) or Weikang Ma (wma6@iit.edu).
Confirmed speakers (Alphabetically):
Alice Arcidiacono (King’s College London, UK)
Anthony Hessel (University of Muenster, Germany)
Cameron Hill (King’s College London, UK)
Christopher McAllister (University of Pennsylvania, USA)
Ilaria Morotti (University of Florence, Italy)
Julien Ochala (University of Copenhagen, Denmark)
Kristi Kooiker (University of Washington, USA)
Leonardo Sacconi (Institute of Clinical Physiology-CNR, Italy)
Maicon Landim-Vieira (Illinois Institute of Technology, USA)
Michael Regnier (University of Washington, USA)
Natalia Koubassova (Moscow University, Russia)
Roger Craig (UMass Chan Medical School, USA)
Thomas Irving (BioCAT, Illinois Institute of Technology, USA)
Vincenzo Lombardi (University of Florence, Italy)
Vivek Jani (Johns Hopkins University, USA)
Weikang Ma (BioCAT, Illinois Institute of Technology, USA)
